Study: Cannabinoids Show Promise in Treating Immune System Disorders

[CentralMass]

https://share.newsbreak.com/fnz91p13
"A new review published in the Chinese Medical Journal provides one of the most detailed examinations to date of how cannabinoids interact with the immune system.
The review outlines how cannabinoids, whether derived from marijuana (phytocannabinoids like THC and CBD), produced naturally in the body (endocannabinoids such as anandamide and 2-AG), or synthesized in laboratories, regulate immune activity through a network known as the endocannabinoid system. The study was conducted by researchers at The Fourth Military Medical University, the Air Force Medical University, and Shanghai Jiao Tong University, all in China.
The study notes that the endocannabinoid system consists of receptors, enzymes, and signaling molecules that influence immune responses, inflammation, and cellular survival. Two main receptors, CB1 and CB2, have been identified: CB1 is found largely in the brain, while CB2 is more closely linked to immune cells.
According to the researchers, cannabinoids can suppress immune activity by inducing immune cell death, slowing proliferation, and reducing the release of proinflammatory molecules like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α . In doing so, cannabinoids can help calm overactive immune responses that drive conditions such as multiple sclerosis (MS), rheumatoid arthritis (RA), and inflammatory bowel disease